thrA protein (Streptococcus mitis) - STRING interaction network

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[Homology]

Score

thrA

Homoserine dehydrogenase. (428 aa)

Predicted Functional Partners:

thrB

0.999

asd

0.975

metAA

0.948

smi_1687

0.941

thrC

0.937

dapA

0.932

smi_1508

0.884

metE

0.874

ilvE

0.868

smi_1010

0.857

Your Current Organism:

Streptococcus mitis

NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
asd	dapA	smi_1133	smi_1132	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	0.983
asd	smi_1687	smi_1133	smi_1687	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	Aspartate kinase; COG0527; Belongs to the aspartokinase family.	0.993
asd	thrA	smi_1133	smi_0773	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	Homoserine dehydrogenase.	0.975
asd	thrB	smi_1133	smi_0774	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.	0.681
asd	thrC	smi_1133	smi_0193	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	Threonine synthase.	0.468
dapA	asd	smi_1132	smi_1133	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	0.983
dapA	smi_1687	smi_1132	smi_1687	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	Aspartate kinase; COG0527; Belongs to the aspartokinase family.	0.640
dapA	thrA	smi_1132	smi_0773	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	Homoserine dehydrogenase.	0.932
ilvE	smi_1508	smi_0906	smi_1508	Branched-chain amino acid aminotransferase.	Cystathionine gamma-synthase.	0.927
ilvE	thrA	smi_0906	smi_0773	Branched-chain amino acid aminotransferase.	Homoserine dehydrogenase.	0.868
ilvE	thrB	smi_0906	smi_0774	Branched-chain amino acid aminotransferase.	Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.	0.846
metAA	metE	smi_1566	smi_1600	Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.	Methionine synthase II (cobalamin-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	0.869
metAA	smi_1010	smi_1566	smi_1010	Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.	O-acetylhomoserine sulfhydrylase.	0.962
metAA	smi_1508	smi_1566	smi_1508	Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.	Cystathionine gamma-synthase.	0.983
metAA	smi_1687	smi_1566	smi_1687	Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.	Aspartate kinase; COG0527; Belongs to the aspartokinase family.	0.913
metAA	thrA	smi_1566	smi_0773	Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.	Homoserine dehydrogenase.	0.948
metAA	thrB	smi_1566	smi_0774	Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.	Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.	0.915
metE	metAA	smi_1600	smi_1566	Methionine synthase II (cobalamin-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.	0.869
metE	smi_1010	smi_1600	smi_1010	Methionine synthase II (cobalamin-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	O-acetylhomoserine sulfhydrylase.	0.923
metE	smi_1508	smi_1600	smi_1508	Methionine synthase II (cobalamin-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	Cystathionine gamma-synthase.	0.983