Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
smi_0776ABC transporter, ATP-binding/membrane-spanning protein; COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components. (574 aa)    
Predicted Functional Partners:
smi_0777
ABC transporter ATP-binding/membrane-spanning protein; COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components.
 
  
0.989
glnQ
ABC transporter ATP-binding protein-glutamine transport; COG1126.
 
     
0.780
smi_0154
ABC transporter ATP-binding/membrane spanning protein-unknown substrate.
 
  
0.617
smi_1834
ABC transporter, permease and ATP-binding protein, multidrug export; COG1132, MdlB, ABC-type multidrug transport system.
 
  
0.617
msrA
Methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.608
smi_0537
ABC transporter, ATP-binding domain/permease protein, lipid/multidrug/protein-type ABC exporter.
 
  
0.601
smi_1698
ABC-type multidrug transport system, ATPase and permease components; COG1132.
 
  
0.586
smi_0536
ABC transporter, ATP-binding domain/permease protein, lipid/multidrug/protein-type ABC exporter; MsbA is an ABC transporter, closely related to eukaryotic MDR proteins.
 
  
0.585
rluA3
23S rRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
 
 
   0.561
smi_1076
ABC transporter, ATP-binding protein; COG1136, ABC-type antimicrobial peptide transport system, ATPase component.
 
     
0.481
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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