Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
smi_0791Metal-dependent CAAX amino terminal membrane protease family protein; Pfam02517. (195 aa)    
Predicted Functional Partners:
smi_0790
Conserved hypothetical protein.
       0.865
smi_0788
Conserved hypothetical protein.
       0.850
smi_0789
Conserved hypothetical protein; COG1393, ArsC, Arsenate reductase and related proteins, glutaredoxin family.
       0.850
smi_0787
Methyl transferase.
       0.766
smi_0786
Conserved hypothetical protein; Pfam06970, RepA_N, replication initiator protein A (RepA) N-terminus.
       0.721
smi_0785
Conserved hypothetical protein.
       0.542
smi_1734
Conserved hypothetical protein; COG1286, CvpA, uncharacterized membrane protein.
  
     0.501
smi_0862
Acetyltransferase; Pfam00583, Acetyltransf_1, acetyltransferase (GNAT) family.
  
     0.478
smi_0864
Conserved hypothetical protein; Pfam00293, NUDIX; COG0494, MutT; Belongs to the Nudix hydrolase family.
  
     0.437
smi_1136
GtrA family protein.
  
     0.421
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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