Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_0799Conserved hypothetical protein. (107 aa)    
Predicted Functional Partners:
ppaC
Inorganic pyrophosphatase/exopolyphosphatase; COG1227.
     
  0.900
ntpI
V-type H+-ATPase, subunit I; COG1269, NtpI, archaeal/vacuolar-type H+-ATPase subunit I.
       0.865
ntpK
V-type H+-ATPase, subunit K; COG0636, AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K; Belongs to the V-ATPase proteolipid subunit family.
       0.843
ntpE
V-type H+-ATPase, subunit E.
       0.785
ntpC
V-type H+-ATPase, subunit C; COG1527, NtpC, Archaeal/vacuolar-type H+-ATPase subunit C.
       0.703
ntpF
V-type H+-ATPase, subunit F; COG1436, NtpG, Archaeal/vacuolar-type H+-ATPase subunit F.
       0.703
smi_0798
COG1940, NagC, transcriptional regulator/sugar kinase; pfam00480, ROK.
       0.695
ntpA
V-type H+-ATPase, subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.
       0.644
ntpB
V-type H+-ATPase, subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.
       0.644
ntpD
ATP synthase, subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.
       0.619
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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