Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
smi_0818Conserved hypothetical protein. (176 aa)    
Predicted Functional Partners:
rlmN
Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
       0.830
smi_0820
VanZ-related protein; COG4767, VanZ, glycopeptide antibiotics resistance protein; pfam04892, VanZ like family.
       0.830
smi_1918
Conserved hypothetical protein; Belongs to the UPF0473 family.
  
     0.714
smi_0821
ABC transporter, ATP-binding protein; COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains.
       0.696
rpoE
DNA-dependent RNA Polymerase, delta subunit (RNAP delta factor); Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.
  
     0.676
smi_0940
Conserved hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family.
  
     0.674
dnaI
Primosome component (helicase loader), primosomal protein DnaI.
  
     0.658
smi_1639
Conserved hypothetical protein; COG1161, predicted GTPase.
  
     0.644
smi_0722
COG0647: sugar phosphatases of the HAD superfamily, N-acetyl-glucosamine catabolism protein.
 
  
 0.643
smi_0362
ABC transporter membrane-spanning permease.
  
     0.629
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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