Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
smi_0820VanZ-related protein; COG4767, VanZ, glycopeptide antibiotics resistance protein; pfam04892, VanZ like family. (157 aa)    
Predicted Functional Partners:
rlmN
Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
       0.865
smi_0818
Conserved hypothetical protein.
       0.830
smi_0821
ABC transporter, ATP-binding protein; COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains.
       0.718
smi_1529
Sugar transport protein.
  
     0.600
smi_0675
Major facilitator superfamily transporter-efflux?.
  
     0.470
smi_0314
Methyltransferase.
       0.461
kdtB
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
       0.461
smi_0316
Conserved hypothetical protein; COG3480, SdrC, predicted secreted protein containing a PDZ domain.
       0.461
smi_0536
ABC transporter, ATP-binding domain/permease protein, lipid/multidrug/protein-type ABC exporter; MsbA is an ABC transporter, closely related to eukaryotic MDR proteins.
       0.461
smi_0537
ABC transporter, ATP-binding domain/permease protein, lipid/multidrug/protein-type ABC exporter.
       0.461
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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