Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_0847Conserved hypothetical protein; COG1247, sortase and related acyltransferases. (242 aa)    
Predicted Functional Partners:
smi_0225
Conserved hypothetical protein; Transcriptional regulator, BglG family.
   
    0.926
smi_0844
Conserved hypothetical protein.
       0.856
smi_0845
Pfam00106, adh_short, short chain dehydrogenase; COG1028, FabG.
       0.856
smi_0846
Conserved hypothetical protein.
  
    0.815
smi_0843
Oxidoreductase; COG4989, predicted oxidoreductase.
 
     0.688
smi_0849
Conserved hypothetical protein.
       0.629
smi_0848
Hypothetical protein; COG1437, CyaB, adenylate cyclase.
       0.538
smi_0351
Conserved hypothetical protein.
  
     0.501
mutR
Transcriptional regulator; Cd00093, helix-turn-helix XRE-family.
   
    0.499
smi_1950
Transcriptional regulator; Cd00093, Helix-turn-helix XRE-family like proteins.
   
    0.499
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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