smi_0866 protein (Streptococcus mitis) - STRING interaction network

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Score

smi_0866

Conserved hypothetical protein. (76 aa)

Predicted Functional Partners:

smi_0867

0.714

clpE

0.676

smi_0864

0.666

cotS

0.661

smi_0863

0.630

folD

0.630

nnrD

0.574

smi_0868

0.539

smi_0561

0.492

zwf

0.441

Your Current Organism:

Streptococcus mitis

NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
clpE	folD	smi_0865	smi_0869	ATP-dependent Clp protease, ATP-binding subunit; Belongs to the ClpA/ClpB family.	FolD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.567
clpE	nnrD	smi_0865	smi_0871	ATP-dependent Clp protease, ATP-binding subunit; Belongs to the ClpA/ClpB family.	Conserved hypothetical protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.	0.464
clpE	smi_0863	smi_0865	smi_0863	ATP-dependent Clp protease, ATP-binding subunit; Belongs to the ClpA/ClpB family.	Conserved hypothetical protein.	0.657
clpE	smi_0864	smi_0865	smi_0864	ATP-dependent Clp protease, ATP-binding subunit; Belongs to the ClpA/ClpB family.	Conserved hypothetical protein; Pfam00293, NUDIX; COG0494, MutT; Belongs to the Nudix hydrolase family.	0.770
clpE	smi_0866	smi_0865	smi_0866	ATP-dependent Clp protease, ATP-binding subunit; Belongs to the ClpA/ClpB family.	Conserved hypothetical protein.	0.676
clpE	smi_0867	smi_0865	smi_0867	ATP-dependent Clp protease, ATP-binding subunit; Belongs to the ClpA/ClpB family.	COG0765, HisM, ABC-type amino acid transport system, permease component.	0.570
cotS	smi_0866	smi_0373	smi_0866	Aminoglycoside phosphotransferase.	Conserved hypothetical protein.	0.661
folD	clpE	smi_0869	smi_0865	FolD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	ATP-dependent Clp protease, ATP-binding subunit; Belongs to the ClpA/ClpB family.	0.567
folD	nnrD	smi_0869	smi_0871	FolD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	Conserved hypothetical protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.	0.695
folD	smi_0866	smi_0869	smi_0866	FolD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	Conserved hypothetical protein.	0.630
folD	smi_0867	smi_0869	smi_0867	FolD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	COG0765, HisM, ABC-type amino acid transport system, permease component.	0.719
folD	smi_0868	smi_0869	smi_0868	FolD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component.	0.547
nnrD	clpE	smi_0871	smi_0865	Conserved hypothetical protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.	ATP-dependent Clp protease, ATP-binding subunit; Belongs to the ClpA/ClpB family.	0.464
nnrD	folD	smi_0871	smi_0869	Conserved hypothetical protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.	FolD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.	0.695
nnrD	smi_0866	smi_0871	smi_0866	Conserved hypothetical protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.	Conserved hypothetical protein.	0.574
nnrD	smi_0867	smi_0871	smi_0867	Conserved hypothetical protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.	COG0765, HisM, ABC-type amino acid transport system, permease component.	0.620
smi_0561	smi_0863	smi_0561	smi_0863	Conserved hypothetical protein.	Conserved hypothetical protein.	0.490
smi_0561	smi_0864	smi_0561	smi_0864	Conserved hypothetical protein.	Conserved hypothetical protein; Pfam00293, NUDIX; COG0494, MutT; Belongs to the Nudix hydrolase family.	0.629
smi_0561	smi_0866	smi_0561	smi_0866	Conserved hypothetical protein.	Conserved hypothetical protein.	0.492
smi_0863	clpE	smi_0863	smi_0865	Conserved hypothetical protein.	ATP-dependent Clp protease, ATP-binding subunit; Belongs to the ClpA/ClpB family.	0.657