Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
smi_0875Conserved hypothetical protein. (186 aa)    
Predicted Functional Partners:
deoB
Phosphopentomutase DeoB; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
       0.865
pnp
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
       0.865
smi_0877
Voltage-gated chloride channel family protein, (ClC) family protein; COG0038.
       0.865
rpiA
Ribose-5-phosphate epimerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
       0.823
smi_1424
Conserved hypothetical protein.
  
     0.759
smi_0878
COG0518, GuaA, GMP synthase - glutamine amidotransferase domain.
       0.673
smi_1513
Conserved hypothetical protein; Belongs to the UPF0337 (CsbD) family.
  
     0.470
smi_1345
Conserved hypothetical protein; Pfam00144, beta-lactamase.
       0.461
smi_0549
Acetyltransferase, GNAT family; COG1670, acetyltransferases, including N-acetylases of ribosomal proteins.
  
     0.432
smi_0872
Conserved hypothetical protein.
       0.430
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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