Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
coaAPantothenate kinase; COG1072, CoaA. (306 aa)    
Predicted Functional Partners:
smi_1193
Flavoprotein; Pfam04127, DNA / pantothenate metabolism flavoprotein.
   
 
 0.931
kdtB
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
     
 0.928
smi_1194
Flavoprotein involved in panthothenate metabolism; COG0452, phosphopantothenoylcysteine synthetase/decarboxylase.
   
 
 0.909
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
 
     0.803
flaR
DNA topology modulation protein FlaR.
     
 0.720
aroD
3-dehydroquinate dehydratase, (3-dehydroquinase) (type I DHQase); Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
      
 0.657
dgkA
Diacylglycerol kinase.
      
 0.642
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
      
 0.630
smi_0884
Conserved hypothetical protein.
       0.502
ftsL
Cell division protein FtsL; Essential cell division protein; Belongs to the FtsL family.
      
 0.501
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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