Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_0895COG4603, ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. (318 aa)    
Predicted Functional Partners:
smi_0893
ABC transporter, ATP-binding protein; COG3845, ABC-type uncharacterized transport system, ATPase components.
 
 0.999
smi_0894
ABC transporter, permease protein; COG4603, COG4603, ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.
 
0.998
smi_0892
COG1744, uncharacterized ABC-type transport system; Extracellular protein, signal peptide type I.
 
 
 0.995
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
  
  
 0.743
deoA
COG0213, DeoA, thymidine phosphorylase.
     
 0.734
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
  
  
 0.713
smi_0888
Transposase, authentic stop codon; Pfam01610, ISL3 family.
       0.623
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
       0.461
coaA
Pantothenate kinase; COG1072, CoaA.
       0.461
nox
NADH oxidase.
       0.461
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.