node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gidB | guaB | smi_1243 | smi_2075 | Methyltransferase GidB (glucose inhibited division protein B); Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.467 |
gidB | rnpA | smi_1243 | smi_0215 | Methyltransferase GidB (glucose inhibited division protein B); Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.578 |
gidB | smi_0901 | smi_1243 | smi_0901 | Methyltransferase GidB (glucose inhibited division protein B); Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | Conserved hypothetical protein, truncation. | 0.544 |
gidB | smi_0902 | smi_1243 | smi_0902 | Methyltransferase GidB (glucose inhibited division protein B); Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | Conserved hypothetical protein, truncation. | 0.544 |
gidB | thdF | smi_1243 | smi_1131 | Methyltransferase GidB (glucose inhibited division protein B); Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.890 |
guaB | gidB | smi_2075 | smi_1243 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Methyltransferase GidB (glucose inhibited division protein B); Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.467 |
guaB | smi_0901 | smi_2075 | smi_0901 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Conserved hypothetical protein, truncation. | 0.403 |
guaB | smi_0902 | smi_2075 | smi_0902 | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Conserved hypothetical protein, truncation. | 0.403 |
rnpA | gidB | smi_0215 | smi_1243 | Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | Methyltransferase GidB (glucose inhibited division protein B); Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.578 |
rnpA | smi_0901 | smi_0215 | smi_0901 | Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | Conserved hypothetical protein, truncation. | 0.439 |
rnpA | smi_0902 | smi_0215 | smi_0902 | Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | Conserved hypothetical protein, truncation. | 0.439 |
rnpA | thdF | smi_0215 | smi_1131 | Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.513 |
smi_0901 | gidB | smi_0901 | smi_1243 | Conserved hypothetical protein, truncation. | Methyltransferase GidB (glucose inhibited division protein B); Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.544 |
smi_0901 | guaB | smi_0901 | smi_2075 | Conserved hypothetical protein, truncation. | Inosine monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.403 |
smi_0901 | rnpA | smi_0901 | smi_0215 | Conserved hypothetical protein, truncation. | Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.439 |
smi_0901 | smi_0902 | smi_0901 | smi_0902 | Conserved hypothetical protein, truncation. | Conserved hypothetical protein, truncation. | 0.693 |
smi_0901 | smi_0903 | smi_0901 | smi_0903 | Conserved hypothetical protein, truncation. | Conserved hypothetical protein; Pfam00583, Acetyltransf_1, acetyltransferase (GNAT) family. | 0.616 |
smi_0901 | smi_1182 | smi_0901 | smi_1182 | Conserved hypothetical protein, truncation. | Conserved hypothetical protein. | 0.416 |
smi_0901 | thdF | smi_0901 | smi_1131 | Conserved hypothetical protein, truncation. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.689 |
smi_0901 | topA | smi_0901 | smi_1222 | Conserved hypothetical protein, truncation. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.499 |