Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_0945Conserved hypothetical protein. (264 aa)    
Predicted Functional Partners:
smi_0880
Conserved hypothetical protein.
   
   0.869
smi_0946
Conserved hypothetical protein.
       0.773
smi_0947
Conserved hypothetical protein.
       0.773
smi_0942
Site-specific DNA methylase; COG0270, Dcm.
       0.693
smi_0943
Conserved hypothetical protein.
       0.693
smi_0944
Site-specific DNA methylase; COG0270, Dcm.
       0.693
gid
Gid NAD(FAD)-utilizing enzyme possibly involved in translation; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.
       0.470
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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