STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smi_0953PhoH family protein; COG1702, PhoH, predicted ATPase. (334 aa)    
Predicted Functional Partners:
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.892
recO
Conserved hypothetical protein; Involved in DNA repair and RecF pathway recombination.
  
    0.761
smi_0952
Conserved hypothetical protein; Belongs to the UPF0346 family.
       0.603
smi_0951
Conserved hypothetical protein; Belongs to the CvfB family.
       0.599
smi_0954
Acetyltransferase; COG1670.
       0.543
era
GTPase/GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
 
  
 0.532
cmk
Cytidylate kinase.
 
    0.526
celB
Competence protein CelB.
       0.515
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
       0.498
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
       0.496
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.