Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
smi_0979Hypothetical protein; LPXTG motif. (1218 aa)    
Predicted Functional Partners:
zmpB
Zinc metalloprotease; LPXTG motif.
 
    0.626
monX
Cell wall surface anchor family protein, Ser rich; LPXTG motif.
 
     0.588
nanA
Sialidase A (neuraminidase A); LPXTG motif.
  
     0.570
smi_0345
endo-beta-N-acetylglucosaminidase D; LPXTG motif.
 
 
 0.554
smi_1276
Permease; COG0672, high-affinity Fe2+/Pb2+ permease, membrane protein.
  
     0.521
smi_1705
Acetyl transferase.
  
    0.516
aacA-aphD
Aminoglycoside acetyltransferase and aminoglycoside phosphotransferase; Bifunctional AAC.
 
    0.491
coiA
Competence protein CoiA.
 
     0.486
scpA
Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.477
smi_1317
Hypothetical protein; LPXTG motif.
  
    0.443
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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