Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
smi_0989COG4120, ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. (288 aa)    
Predicted Functional Partners:
smi_0988
ABC transporter, substrate-binding protein; COG2984, ABC-type uncharacterized transport system.
    0.990
smi_0990
ABC transporter, ATP-binding protein; COG1101, ABC-type uncharacterized transport system, ATPase component.
 
    0.980
smi_0327
ABC transporter, substrate binding protein; COG2984, ABC-type transport system.
    0.967
smi_0329
ABC-type uncharacterized transport system, ATPase component COG1101.
 
    0.873
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
       0.585
rpoD
DNA-dependent RNA Polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
       0.585
smi_0993
Conserved hypothetical protein.
       0.560
pavA
Adherence and virulence protein A.
       0.461
rnj
Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
       0.461
smi_1585
Esterase; COG0627.
       0.456
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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