Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pepXXaa-Pro dipeptidyl-peptidase; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidase S15 family. (760 aa)    
Predicted Functional Partners:
pepN
Aminopeptidase N.
 
   
 0.887
pepQ
X-Pro dipeptidase.
  
   
 0.774
smi_0639
Peptidase M13 superfamily; COG3590, metalloendopeptidase.
      
 0.724
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
      
 0.724
smi_1577
Peptidase M20 superfamily.
      
 0.724
pepP
COG0006, Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family.
  
   
 0.682
smi_1345
Conserved hypothetical protein; Pfam00144, beta-lactamase.
 
     0.667
smi_1347
Glycerol uptake facilitator paralog; Cd00333, Major intrinsic protein (MIP) superfamily; Belongs to the MIP/aquaporin (TC 1.A.8) family.
 
   
 0.665
pepC
Aminopeptidase C; Belongs to the peptidase C1 family.
  
   
 0.655
smi_1779
Oligopeptide permease; COG3104, PTR2, Dipeptide/tripeptide permease, proton-dependent transport.
 
   
 0.623
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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