Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lacDTagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family. (326 aa)    
Predicted Functional Partners:
lacC
Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.997
lacB
Galactose-6-phosphate isomerase, LacB subunit.
 
  
 0.964
lacA
Galactose-6-phosphate isomerase, LacA subunit.
  
  
 0.918
pfkA
6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.911
lacE
PTS system, lactose-specific IIBC component.
 
  
 0.881
agaS
Tagatose-6-phosphate ketose/aldose isomerase.
 
     0.815
smi_1025
LacX; COG2017, GalM, galactose mutarotase and related enzymes.
  
  
 0.782
smi_1023
PTS system, IIB component; COG3414, SgaB, galactitol-specific IIB.
 
     0.734
lacF
PTS system, lactose-specific IIA component.
  
  
 0.732
codY
GTP-sensing transcriptional pleiotropic repressor; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
      
 0.724
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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