Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mutTMutator mutT protein; 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase; Belongs to the Nudix hydrolase family. (154 aa)    
Predicted Functional Partners:
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
       0.859
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
       0.850
smi_1058
Na+-driven multidrug efflux pump; COG0534, NorM.
  
    0.767
mutS2
Mismatch repair ATPase (MutS family); Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
     
 0.645
smi_0387
Acetyltransferase, GNAT family; COG1670, RimL, acetyltransferases, including N-acetylases of ribosomal proteins.
 
 
    0.643
smi_1054
Hydrolase, haloacid dehalogenase-like family; COG1011.
  
    0.606
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
     
 0.596
smi_0562
7,8-dihydro-8-oxoguanine-triphosphatase.
      
 0.548
smi_1178
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
  
  
 0.487
smi_0740
Alpha-acetolactate decarboxylase.
       0.461
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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