Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_1101Conserved hypothetical protein; Pfam06414, Zeta toxin. (256 aa)    
Predicted Functional Partners:
smi_1102
Transcriptional regulator; Pfam01381, Helix-turn-helix.
 
 
 
 0.998
smi_1991
Conserved hypothetical protein; Related to bacteriocin immunity proteins.
  
 
   0.418
smi_1103
Conserved hypothetical protein.
       0.414
smi_0056
Conserved hypothetical protein.
   
 
 0.412
rgg
Positive transcriptional regulator of glucosyltransferase and Spp phenotype.
   
 
 0.412
rggD
Transcriptional regulators, MutR family; COG1396.
   
 
 0.412
mutR
Transcriptional regulator; Cd00093, helix-turn-helix XRE-family.
   
 
 0.412
smi_1470
Transcriptional regulator; COG1396.
   
 
 0.412
smi_1732
Transcriptional regulator; Cd00093, HTH_XRE, helix-turn-helix XRE-family like proteins.
   
 
 0.412
smi_1950
Transcriptional regulator; Cd00093, Helix-turn-helix XRE-family like proteins.
   
 
 0.412
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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