Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nplTNeopullulanase; Belongs to the glycosyl hydrolase 13 family. (581 aa)    
Predicted Functional Partners:
malM
4-alpha-glucanotransferase (amylomaltase).
 
 
 0.988
pulA
Pullulanase; Belongs to the glycosyl hydrolase 13 family.
 
 0.984
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
 
 0.968
malP
Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 0.961
smi_0750
Alpha-amylase; Belongs to the glycosyl hydrolase 13 family.
  
  
0.905
smi_1403
Conserved hypothetical protein; COG3568, metal-dependent hydrolase.
  
 
  0.904
smi_1848
COG1523, pullulanase PulA and related glycosidases, LPXTG motif.
  
0.888
malX
malX-protein, ABC transporter substrate-binding protein-maltose/maltodextrin.
 
  
 0.876
malD
malD-protein, ABC transporter membrane-spanning permease-maltose/maltodextrin.
 
  
 0.828
malC
malC-protein, ABC transporter membrane-spanning permease-maltose/maltodextrin.
 
  
 0.822
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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