Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_1118Conserved hypothetical protein. (188 aa)    
Predicted Functional Partners:
vncS
Histidine kinase.
 
     0.644
vexp3
ABC transporter, permease.
  
     0.605
vexp1
ABC transporter, permease; COG4591, ABC-type transport system, involved in lipoprotein release.
  
     0.562
vncR
DNA-binding response regulator.
  
     0.481
smi_1119
Conserved hypothetical protein; COG2265, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
       0.474
smi_1120
Conserved hypothetical protein; COG4086, excreted protein, signal peptide type I.
 
     0.470
vex2
ABC transporter ATP-binding protein.
  
     0.435
smi_0549
Acetyltransferase, GNAT family; COG1670, acetyltransferases, including N-acetylases of ribosomal proteins.
  
     0.434
smi_1117
Conserved hypothetical protein.
       0.400
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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