| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| mutR | smi_1172 | smi_1171 | smi_1172 | Transcriptional regulator; Cd00093, helix-turn-helix XRE-family. | ABC transporter ATP-binding protein-unknown substrate; COG0488, ATPase components of ABC transporters with duplicated ATPase domains. | 0.844 |
| rplC | rplD | smi_1905 | smi_1904 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.999 |
| rplC | rplP | smi_1905 | smi_1898 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.999 |
| rplC | rplU | smi_1905 | smi_0926 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.991 |
| rplC | rpmD | smi_1905 | smi_1887 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 50S ribosomal protein L30. | 0.997 |
| rplC | rpmH | smi_1905 | smi_0290 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. | 0.966 |
| rplC | rpsC | smi_1905 | smi_1899 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.999 |
| rplC | rpsO | smi_1905 | smi_0656 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.984 |
| rplC | rpsS | smi_1905 | smi_1901 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.999 |
| rplC | smi_1172 | smi_1905 | smi_1172 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | ABC transporter ATP-binding protein-unknown substrate; COG0488, ATPase components of ABC transporters with duplicated ATPase domains. | 0.804 |
| rplD | rplC | smi_1904 | smi_1905 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.999 |
| rplD | rplP | smi_1904 | smi_1898 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.999 |
| rplD | rplU | smi_1904 | smi_0926 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.992 |
| rplD | rpmD | smi_1904 | smi_1887 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 50S ribosomal protein L30. | 0.998 |
| rplD | rpmH | smi_1904 | smi_0290 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. | 0.967 |
| rplD | rpsC | smi_1904 | smi_1899 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.999 |
| rplD | rpsO | smi_1904 | smi_0656 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.995 |
| rplD | rpsS | smi_1904 | smi_1901 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.999 |
| rplD | smi_1172 | smi_1904 | smi_1172 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | ABC transporter ATP-binding protein-unknown substrate; COG0488, ATPase components of ABC transporters with duplicated ATPase domains. | 0.801 |
| rplP | rplC | smi_1898 | smi_1905 | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.999 |