Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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gene co-occurrence
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[Homology]
Score
vicXConserved protein VicX; Pfam00753, metallo-beta-lactamase superfamily. (269 aa)    
Predicted Functional Partners:
smi_1177
COG0745, response regulator, OmpR family.
  
  
 0.958
smi_1176
Histidine kinase; COG5002, VicK, signal transduction histidine kinase.
  
  
 0.874
smi_1178
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
       0.696
smi_0649
DNA-binding response regulator.
  
  
 0.591
smi_1588
ABC-type polar amino acid transport system, ATPase component, glutamine transport; COG1126.
  
    0.484
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
     
 0.482
polI
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.479
smi_0093
Histidine kinase.
  
  
 0.473
smc
Chromosome condensation and segregation SMC protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
  
    0.469
smi_1590
ABC-type amino acid transporter, permease component; COG0765; Belongs to the binding-protein-dependent transport system permease family.
       0.461
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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