Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_1196Conserved hypothetical protein. (175 aa)    
Predicted Functional Partners:
smi_1197
Conserved hypothetical protein; Pfam02829, 3H domain, three conserved histidine residues.
 
   
 0.882
smi_1195
Membrane protein; COG4684.
 
     0.636
smi_1194
Flavoprotein involved in panthothenate metabolism; COG0452, phosphopantothenoylcysteine synthetase/decarboxylase.
       0.457
smi_1186
Conserved hypothetical protein.
  
     0.450
smi_1193
Flavoprotein; Pfam04127, DNA / pantothenate metabolism flavoprotein.
       0.446
nadD
Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
      
 0.435
gpmA-2
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (phosphoglyceromutase); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
       0.420
pbp2B
Penicillin-binding protein 2B.
       0.414
smi_0347
Conserved hypothetical protein.
  
     0.410
recR
Recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
       0.404
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.