Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_1202Conserved hypothetical protein; Pfam02517, CAAX amino terminal protease family. (317 aa)    
Predicted Functional Partners:
glnP
ABC transporter membrane spanning permease-glutamine transport; COG0765.
  
  
 0.877
glnQ
ABC transporter ATP-binding protein-glutamine transport; COG1126.
     
 0.876
uvrB
Excinuclease ABC-subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.749
smi_1151
Conserved hypothetical protein; COG1307, uncharacterized protein, DegV family.
      
 0.615
smi_0204
Conserved hypothetical protein.
      
 0.606
smi_1172
ABC transporter ATP-binding protein-unknown substrate; COG0488, ATPase components of ABC transporters with duplicated ATPase domains.
      
 0.599
smi_1199
Pfam00583, acetyltransferase (GNAT) family.
       0.578
smi_0684
Nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
      
 0.575
smi_1200
Acetyltransferase; COG1670.
       0.563
smi_1096
Conserved hypothetical protein; COG0560, SerB, phosphoserine phosphatase.
  
     0.530
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.