Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
smi_1263Conserved hypothetical protein; COG3077, DNA-damage-inducible protein, RelB domain. (86 aa)    
Predicted Functional Partners:
smi_0265
Conserved hypothetical protein.
 
 
 0.962
smi_0697
Conserved hypothetical protein; Plasmid stabilization system antitoxin protein.
  
     0.749
smi_1261
Hypothetical protein; COG2361.
 
     0.686
smi_1262
Conserved hypothetical protein; COG1669, nucleotidyltransferase domain.
 
     0.673
smi_0698
Plasmid stabilization system toxin protein, RelE/ParE family protein; COG1185: polyribonucleotide nucleotidyltransferase.
 
 
   0.513
smi_1273
Conserved hypothetical protein.
   
   0.438
smi_1260
Site-specific recombinase, phage integrase family, N-terminal truncation; Cd01189, phiLC3 phage and phage-related integrases.
       0.419
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
       0.409
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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