Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
smi_1278Iron transport, substrate-binding lipoprotein; COG2822. (290 aa)    
Predicted Functional Partners:
smi_1276
Permease; COG0672, high-affinity Fe2+/Pb2+ permease, membrane protein.
 
  
 0.994
smi_1277
Peroxidase; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family.
 
  
 0.992
tatA
Sec-independent protein translocase protein tatA.
 
   
 0.886
tatC
Sec-independent protein translocase tatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes.
 
     0.883
tehB
Tellurite resistance protein TehB.
  
     0.420
smi_0257
Conserved hypothetical protein; ABC transporter permease protein.
  
     0.414
eriC
Voltage-gated chloride channel family protein EriC.
       0.401
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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