gpmA protein (Streptococcus mitis) - STRING interaction network

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Score

gpmA

Phosphoglycerate mutase. (205 aa)

Predicted Functional Partners:

smi_1294

0.867

smi_1293

0.865

smi_1292

0.732

gpmA-2

0.696

lysS

0.674

eno

0.545

pgk

0.538

smi_1290

0.529

gcaD

0.414

smi_1289

0.410

Your Current Organism:

Streptococcus mitis

NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
eno	gpmA	smi_1159	smi_1295	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.	Phosphoglycerate mutase.	0.545
eno	gpmA-2	smi_1159	smi_0629	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (phosphoglyceromutase); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.	0.980
eno	pgk	smi_1159	smi_0346	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.	Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.	0.992
gcaD	gpmA	smi_1291	smi_1295	UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Phosphoglycerate mutase.	0.414
gcaD	smi_1289	smi_1291	smi_1289	UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Conserved hypothetical protein.	0.859
gcaD	smi_1290	smi_1291	smi_1290	UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Conserved hypothetical protein; Pfam00293, NUDIX domain.	0.884
gcaD	smi_1292	smi_1291	smi_1292	UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Lysozyme; COG3757, lyzozyme M1 (1,4-beta-N-acetylmuramidase).	0.612
gcaD	smi_1293	smi_1291	smi_1293	UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Conserved hypothetical protein; COG2035, predicted membrane protein.	0.412
gcaD	smi_1294	smi_1291	smi_1294	UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Regulatory protein; Pfam04073, prolyl-tRNA synthetases associated domain; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.	0.414
gpmA	eno	smi_1295	smi_1159	Phosphoglycerate mutase.	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.	0.545
gpmA	gcaD	smi_1295	smi_1291	Phosphoglycerate mutase.	UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.414
gpmA	gpmA-2	smi_1295	smi_0629	Phosphoglycerate mutase.	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (phosphoglyceromutase); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.	0.696
gpmA	lysS	smi_1295	smi_1296	Phosphoglycerate mutase.	Lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.	0.674
gpmA	pgk	smi_1295	smi_0346	Phosphoglycerate mutase.	Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.	0.538
gpmA	smi_1289	smi_1295	smi_1289	Phosphoglycerate mutase.	Conserved hypothetical protein.	0.410
gpmA	smi_1290	smi_1295	smi_1290	Phosphoglycerate mutase.	Conserved hypothetical protein; Pfam00293, NUDIX domain.	0.529
gpmA	smi_1292	smi_1295	smi_1292	Phosphoglycerate mutase.	Lysozyme; COG3757, lyzozyme M1 (1,4-beta-N-acetylmuramidase).	0.732
gpmA	smi_1293	smi_1295	smi_1293	Phosphoglycerate mutase.	Conserved hypothetical protein; COG2035, predicted membrane protein.	0.865
gpmA	smi_1294	smi_1295	smi_1294	Phosphoglycerate mutase.	Regulatory protein; Pfam04073, prolyl-tRNA synthetases associated domain; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.	0.867
gpmA-2	eno	smi_0629	smi_1159	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (phosphoglyceromutase); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.	0.980