Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_1368Conserved hypothetical protein. (360 aa)    
Predicted Functional Partners:
smi_1367
cI-like repressor, S. pneumoniae bacteriophage EJ-1; COG2932, predicted transcriptional regulator.
  
    0.747
rny
Conserved hypothetical protein; Endoribonuclease that initiates mRNA decay.
   
    0.589
smi_1366
Conserved hypothetical protein; Similar to S. pneumoniae bacteriophage EJ-1.
       0.499
pavA
Adherence and virulence protein A.
  
    0.493
smi_1292
Lysozyme; COG3757, lyzozyme M1 (1,4-beta-N-acetylmuramidase).
  
     0.480
adcR
Zn(2+)-responsive AdcR transcriptional repressor; Pfam01047, MarR family.
  
     0.411
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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