Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
smi_1403Conserved hypothetical protein; COG3568, metal-dependent hydrolase. (271 aa)    
Predicted Functional Partners:
ptsG
PTS glucose-specific enzyme IIABC component.
 
  
 0.994
malM
4-alpha-glucanotransferase (amylomaltase).
  
 
 0.934
smi_0750
Alpha-amylase; Belongs to the glycosyl hydrolase 13 family.
 
 
  0.915
nplT
Neopullulanase; Belongs to the glycosyl hydrolase 13 family.
  
 
  0.904
smi_0917
Selenocysteine lyase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
    
   0.797
smi_1350
Conserved hypothetical protein.
 
     0.567
smi_1352
Hydrolase; COG2819, predicted hydrolase of the alpha/beta superfamily.
  
    0.551
smi_1615
PTS system; COG1263.
     
 0.529
smi_1351
Conserved hypothetical protein.
  
     0.495
smi_0561
Conserved hypothetical protein.
 
     0.487
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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