Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
smi_1416Conserved hypothetical protein. (91 aa)    
Predicted Functional Partners:
livJ
ABC transporter substrate binding lipoprotein-branched chain amino acid transport.
       0.751
clpP
ATP-dependent CLP protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
       0.747
livF
ABC transporter ATP-binding protein-branched chain amino acid transport.
       0.650
livG
ABC transporter ATP-binding protein-branched chain amino acid transport.
       0.650
livM
ABC transporter membrane-spanning permease-branched chain amino acid transport; Belongs to the binding-protein-dependent transport system permease family.
       0.650
livH
ABC transporter membrane-spanning permease-branched chain amino acid transport; Belongs to the binding-protein-dependent transport system permease family.
       0.650
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
       0.632
smi_1410
Conserved hypothetical protein; D04585, CBS pair ACT assoc2, this cd contains two tandem repeats of the cystathionin.
       0.570
smi_0314
Methyltransferase.
  
  
 0.567
smi_0940
Conserved hypothetical protein; Involved in initiation control of chromosome replication. Belongs to the YabA family.
 
     0.536
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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