| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| atpA | clpP | smi_1311 | smi_1417 | Proton-translocating ATPase, F1 sector, alpha-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | ATP-dependent CLP protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.747 |
| atpA | clpX | smi_1311 | smi_1559 | Proton-translocating ATPase, F1 sector, alpha-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | ATP-dependent Clp protease ATP-binding subunit clpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.733 |
| atpA | groEL | smi_1311 | smi_0482 | Proton-translocating ATPase, F1 sector, alpha-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | CH60_SMI 60 kDa chaperonin (protein Cpn60); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.806 |
| atpA | groES | smi_1311 | smi_0481 | Proton-translocating ATPase, F1 sector, alpha-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | CH10_SMI 10 kDa chaperonin (protein Cpn10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.479 |
| atpA | polI | smi_1311 | smi_0048 | Proton-translocating ATPase, F1 sector, alpha-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.476 |
| clpC | clpP | smi_2045 | smi_1417 | COG0542, ClpA, ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | ATP-dependent CLP protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.966 |
| clpC | clpX | smi_2045 | smi_1559 | COG0542, ClpA, ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease ATP-binding subunit clpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.800 |
| clpC | groEL | smi_2045 | smi_0482 | COG0542, ClpA, ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | CH60_SMI 60 kDa chaperonin (protein Cpn60); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.619 |
| clpC | groES | smi_2045 | smi_0481 | COG0542, ClpA, ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | CH10_SMI 10 kDa chaperonin (protein Cpn10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.737 |
| clpE | clpP | smi_0865 | smi_1417 | ATP-dependent Clp protease, ATP-binding subunit; Belongs to the ClpA/ClpB family. | ATP-dependent CLP protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.971 |
| clpE | clpX | smi_0865 | smi_1559 | ATP-dependent Clp protease, ATP-binding subunit; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease ATP-binding subunit clpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.706 |
| clpE | groEL | smi_0865 | smi_0482 | ATP-dependent Clp protease, ATP-binding subunit; Belongs to the ClpA/ClpB family. | CH60_SMI 60 kDa chaperonin (protein Cpn60); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.573 |
| clpE | groES | smi_0865 | smi_0481 | ATP-dependent Clp protease, ATP-binding subunit; Belongs to the ClpA/ClpB family. | CH10_SMI 10 kDa chaperonin (protein Cpn10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.573 |
| clpL | clpP | smi_1765 | smi_1417 | ATP-dependent Clp protease, ATP-binding subunit; COG0542; Belongs to the ClpA/ClpB family. | ATP-dependent CLP protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.950 |
| clpL | clpX | smi_1765 | smi_1559 | ATP-dependent Clp protease, ATP-binding subunit; COG0542; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease ATP-binding subunit clpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.608 |
| clpL | groEL | smi_1765 | smi_0482 | ATP-dependent Clp protease, ATP-binding subunit; COG0542; Belongs to the ClpA/ClpB family. | CH60_SMI 60 kDa chaperonin (protein Cpn60); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.810 |
| clpL | groES | smi_1765 | smi_0481 | ATP-dependent Clp protease, ATP-binding subunit; COG0542; Belongs to the ClpA/ClpB family. | CH10_SMI 10 kDa chaperonin (protein Cpn10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.613 |
| clpP | atpA | smi_1417 | smi_1311 | ATP-dependent CLP protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Proton-translocating ATPase, F1 sector, alpha-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | 0.747 |
| clpP | clpC | smi_1417 | smi_2045 | ATP-dependent CLP protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | COG0542, ClpA, ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.966 |
| clpP | clpE | smi_1417 | smi_0865 | ATP-dependent CLP protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.971 |