Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_1429ABC transporter, ATP binding domain/permease protein; COG1132, ABC-type multidrug transport system, ATPase and permease components. (524 aa)    
Predicted Functional Partners:
smi_0153
ABC transporter, ATP-binding/permease protein.
  
0.561
smi_0192
Conserved hypothetical protein; Glutamylcysteine synthetase.
  
    0.520
smi_0957
ABC transporter, ATP-binding protein; COG1131, CcmA, ABC-type multidrug transport system, ATPase component.
  
  0.506
smi_0776
ABC transporter, ATP-binding/membrane-spanning protein; COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components.
  
   0.470
smi_1835
ABC transporter, ATP-binding protein, multidrug export; COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease component.
  
   0.470
smi_1977
Transcriptional regulator; Cd00093, Helix-turn-helix XRE-family like proteins.
  
     0.437
smi_1428
Conserved hypothetical protein.
       0.422
smi_1440
ABC transporter ATP-binding protein-unknown substrate; COG1131, ABC-type multidrug transport system, ATPase component.
  
  0.422
comA
Transport ATP-binding protein ComA.
 
 
  
0.421
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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