smi_1434 protein (Streptococcus mitis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

smi_1434

Transcriptional regulator; COG3682. (131 aa)

Predicted Functional Partners:

ctpA

0.871

smi_1433

0.857

adcR

0.796

smi_0518

0.669

merA

0.668

cutC

0.538

smi_1934

0.522

spxB

0.512

adcB

0.511

mntH

0.493

Your Current Organism:

Streptococcus mitis

NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
adcB	adcR	smi_2025	smi_2027	ABC zinc transporter permease; COG1108, ABC-type Mn2+/Zn2+ transport systems.	Zn(2+)-responsive AdcR transcriptional repressor; Pfam01047, MarR family.	0.999
adcB	smi_1434	smi_2025	smi_1434	ABC zinc transporter permease; COG1108, ABC-type Mn2+/Zn2+ transport systems.	Transcriptional regulator; COG3682.	0.511
adcR	adcB	smi_2027	smi_2025	Zn(2+)-responsive AdcR transcriptional repressor; Pfam01047, MarR family.	ABC zinc transporter permease; COG1108, ABC-type Mn2+/Zn2+ transport systems.	0.999
adcR	smi_0518	smi_2027	smi_0518	Zn(2+)-responsive AdcR transcriptional repressor; Pfam01047, MarR family.	Cation diffusion facilitator transporter-heavy metal transport, cation efflux system protein.	0.573
adcR	smi_1434	smi_2027	smi_1434	Zn(2+)-responsive AdcR transcriptional repressor; Pfam01047, MarR family.	Transcriptional regulator; COG3682.	0.796
ctpA	merA	smi_1432	smi_0886	P-type ATPase-probable copper transporter; COG0474, Cation transport ATPase.	Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.833
ctpA	smi_1433	smi_1432	smi_1433	P-type ATPase-probable copper transporter; COG0474, Cation transport ATPase.	COG4633, uncharacterized protein conserved in bacteria.	0.817
ctpA	smi_1434	smi_1432	smi_1434	P-type ATPase-probable copper transporter; COG0474, Cation transport ATPase.	Transcriptional regulator; COG3682.	0.871
ctpA	spxB	smi_1432	smi_1431	P-type ATPase-probable copper transporter; COG0474, Cation transport ATPase.	Pyruvate oxidase; Belongs to the TPP enzyme family.	0.582
cutC	smi_1434	smi_1220	smi_1434	Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family.	Transcriptional regulator; COG3682.	0.538
merA	ctpA	smi_0886	smi_1432	Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	P-type ATPase-probable copper transporter; COG0474, Cation transport ATPase.	0.833
merA	smi_0518	smi_0886	smi_0518	Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Cation diffusion facilitator transporter-heavy metal transport, cation efflux system protein.	0.415
merA	smi_1433	smi_0886	smi_1433	Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	COG4633, uncharacterized protein conserved in bacteria.	0.903
merA	smi_1434	smi_0886	smi_1434	Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Transcriptional regulator; COG3682.	0.668
mntH	smi_1434	smi_1232	smi_1434	Manganese transport protein; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.	Transcriptional regulator; COG3682.	0.493
smi_0518	adcR	smi_0518	smi_2027	Cation diffusion facilitator transporter-heavy metal transport, cation efflux system protein.	Zn(2+)-responsive AdcR transcriptional repressor; Pfam01047, MarR family.	0.573
smi_0518	merA	smi_0518	smi_0886	Cation diffusion facilitator transporter-heavy metal transport, cation efflux system protein.	Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.415
smi_0518	smi_1434	smi_0518	smi_1434	Cation diffusion facilitator transporter-heavy metal transport, cation efflux system protein.	Transcriptional regulator; COG3682.	0.669
smi_1433	ctpA	smi_1433	smi_1432	COG4633, uncharacterized protein conserved in bacteria.	P-type ATPase-probable copper transporter; COG0474, Cation transport ATPase.	0.817
smi_1433	merA	smi_1433	smi_0886	COG4633, uncharacterized protein conserved in bacteria.	Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.903