Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_1457COG2197, response regulator of regulon involved in salavaricin-like lantibiotics. (198 aa)    
Predicted Functional Partners:
smi_1458
COG4585, histidine kinase of regulon involved in salavaricin-like lantibiotics.
 
 0.989
smi_1742
Histidine kinase; COG4585.
 
 
 0.869
smi_0258
Histidine kinase.
 
 
 0.868
smi_1459
ABC transporter, permease; ABC-type antimicrobial peptide transport system.
  
    0.559
smi_1460
ABC-type antimicrobial peptide transport system, ATPase component; COG1136.
       0.545
smi_0257
Conserved hypothetical protein; ABC transporter permease protein.
 
   
 0.536
smi_1456
Conserved hypothetical protein.
       0.533
smi_1455
Rhodanese-related sulfurtransferase; COG0607.
  
  
 0.456
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.