Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
smi_1459ABC transporter, permease; ABC-type antimicrobial peptide transport system. (671 aa)    
Predicted Functional Partners:
smi_1460
ABC-type antimicrobial peptide transport system, ATPase component; COG1136.
 
 
 0.890
smi_0650
Histidine kinase.
 
   
 0.754
smi_1076
ABC transporter, ATP-binding protein; COG1136, ABC-type antimicrobial peptide transport system, ATPase component.
 
 
 0.721
smi_1458
COG4585, histidine kinase of regulon involved in salavaricin-like lantibiotics.
  
    0.568
smi_1457
COG2197, response regulator of regulon involved in salavaricin-like lantibiotics.
  
    0.559
acrA
Conserved hypothetical protein; COG0845, efflux transporter.
  
 
 0.557
smi_0649
DNA-binding response regulator.
 
     0.530
comB
Competence factor transport protein ComB.
  
  
 0.527
smi_0007
Conserved hypothetical protein.
   
    0.452
spiH
Histidine kinase; Peptide pheromone receptor, ComD type.
  
     0.452
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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