Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
ccdA2Cytochrome c biogenesis protein CcdA; COG0785. (236 aa)    
Predicted Functional Partners:
smi_1487
Conserved hypothetical protein; COG2143, thioredoxin-related protein.
  
 0.993
smi_1145
Conserved hypothetical protein; COG0526, thiol-disulfide isomerase and thioredoxins.
  
 0.975
msrA-2
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.817
smi_1485
Response regulator; COG4753.
 
   
 0.669
smi_1484
Histidine kinase; COG2972.
     
 0.605
zmpB
Zinc metalloprotease; LPXTG motif.
       0.401
smi_1483
Conserved hypothetical protein; Belongs to the UPF0340 family.
       0.401
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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