apt protein (Streptococcus mitis) - STRING interaction network

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apt

Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa)

Predicted Functional Partners:

purH

0.978

purB

0.961

deoD

0.928

adk

0.919

pnp

0.914

purM

0.746

purK

0.741

guaA

0.735

purA

0.724

purD

0.701

Your Current Organism:

Streptococcus mitis

NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
adk	apt	smi_1884	smi_1567	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.919
adk	guaA	smi_1884	smi_1342	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	GMP-synthase; Catalyzes the synthesis of GMP from XMP.	0.416
adk	purA	smi_1884	smi_0022	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.616
adk	purB	smi_1884	smi_0076	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.932
adk	purK	smi_1884	smi_0075	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Phosphoribosyl glucinamide formyltransferase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).	0.465
apt	adk	smi_1567	smi_1884	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.919
apt	deoD	smi_1567	smi_0879	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Purine-nucleoside phosphorylase DeoD; COG0813.	0.928
apt	guaA	smi_1567	smi_1342	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	GMP-synthase; Catalyzes the synthesis of GMP from XMP.	0.735
apt	pnp	smi_1567	smi_0876	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.914
apt	purA	smi_1567	smi_0022	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.724
apt	purB	smi_1567	smi_0076	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.961
apt	purD	smi_1567	smi_0073	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Phosphoribosylglycinamide synthetase; Belongs to the GARS family.	0.701
apt	purH	smi_1567	smi_0072	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Phosphoribosylaminoimidazolecarboxamide formyltransferase.	0.978
apt	purK	smi_1567	smi_0075	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Phosphoribosyl glucinamide formyltransferase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).	0.741
apt	purM	smi_1567	smi_0069	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Phosphoribosylformylglycinamide cyclo-ligase.	0.746
deoD	apt	smi_0879	smi_1567	Purine-nucleoside phosphorylase DeoD; COG0813.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.928
deoD	pnp	smi_0879	smi_0876	Purine-nucleoside phosphorylase DeoD; COG0813.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.974
guaA	adk	smi_1342	smi_1884	GMP-synthase; Catalyzes the synthesis of GMP from XMP.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.416
guaA	apt	smi_1342	smi_1567	GMP-synthase; Catalyzes the synthesis of GMP from XMP.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.735
guaA	pnp	smi_1342	smi_0876	GMP-synthase; Catalyzes the synthesis of GMP from XMP.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.624

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