Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
smi_1572Conserved hypothetical protein; COG0537. (156 aa)    
Predicted Functional Partners:
smi_1573
Conserved hypothetical protein; COG1363, FrvX, cellulase M and related proteins.
  
    0.866
vanYb
Carboxypeptidase; Penicillin-insensitive metallo-DD-carboxypeptidase.
       0.791
glnA
Glutamine synthetase type 1.
  
   0.514
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
   
   0.480
smi_0880
Conserved hypothetical protein.
  
 
  0.476
rnmV
Conserved hypothetical protein; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
       0.461
rplK
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
    0.448
smi_1574
Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.
       0.443
smi_0117
Conserved hypothetical protein.
  
    0.412
smi_0345
endo-beta-N-acetylglucosaminidase D; LPXTG motif.
 
    0.402
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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