Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
smi_1573Conserved hypothetical protein; COG1363, FrvX, cellulase M and related proteins. (345 aa)    
Predicted Functional Partners:
smi_1572
Conserved hypothetical protein; COG0537.
  
    0.866
vanYb
Carboxypeptidase; Penicillin-insensitive metallo-DD-carboxypeptidase.
       0.791
smi_1935
NrdI family protein; COG1780, proteins involved in ribonucleotide reduction; Belongs to the NrdI family.
       0.461
smi_1574
Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.
       0.443
birA
Bifunctional protein, biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
       0.434
rplK
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
       0.427
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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