Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_1611Hypothetical protein. (418 aa)    
Predicted Functional Partners:
smi_1610
Hypothetical protein.
       0.773
smi_1606
Restriction endonuclease S subunit; COG0732.
       0.528
smi_1609
Type I restriction-modification system DNA methylase; COG0286.
       0.511
smi_1612
Conserved hypothetical protein, truncation.
       0.511
smi_1607
Restriction endonuclease S subunit.
       0.501
smi_1608
Conserved hypothetical protein; COG3943, virulence protein.
       0.501
smi_1605
Type I restriction-modification system specificity determinant.
       0.400
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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