Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
smi_1615PTS system; COG1263. (628 aa)    
Predicted Functional Partners:
smi_1616
Glycosyl hydrolases family 32; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
 
 
 0.998
ptsG
PTS glucose-specific enzyme IIABC component.
 
 
0.996
smi_1537
N-acetyl-beta-hexosaminidase; COG3525, LPXTG motif.
  
  
 0.992
smi_1996
Glycosyl hydrolase family 20 (GH20) protein.
  
  
 0.992
ptsH
Phosphocarrier protein HPr.
  
 0.991
fruA
PTS system, fructose specific IIBC component.
 
  
 0.987
ptsI
Phosphoenolpyruvate-protein phosphotransferase, PTS enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.973
smi_1614
Transcriptional regulator/sugar kinase; COG1940.
  
 
 0.970
glk
Glucose kinase; COG1940.
  
 
 0.928
smi_0108
Transcriptional regulator, BglG family.
  
 
 0.916
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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