Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
smi_1616Glycosyl hydrolases family 32; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. (484 aa)    
Predicted Functional Partners:
smi_1615
PTS system; COG1263.
 
 
 0.998
smi_1614
Transcriptional regulator/sugar kinase; COG1940.
  
 
 0.978
smi_1617
Transcriptional regulator; COG1609.
 
  
 0.934
ptsG
PTS glucose-specific enzyme IIABC component.
 
  
 0.922
smi_1851
Pfam00232, glycosyl hydrolase family 1; Belongs to the glycosyl hydrolase 1 family.
   
 
 0.913
smi_0229
Conserved hypothetical protein; Phosphotyrosine protein phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.792
fruA
PTS system, fructose specific IIBC component.
   
  
 0.713
fruB
Fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
  
   
 0.657
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
   
  
 0.583
pmi
Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family.
     
 0.580
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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