Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
sstTPredicted Na+/serine symporter; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (401 aa)    
Predicted Functional Partners:
smi_1642
Conserved hypothetical protein; COG0668, MscS, small-conductance mechanosensitive channel.
       0.695
xerC
Integrase/ recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.
      
 0.649
smi_1644
Conserved hypothetical protein.
       0.628
smi_1722
Na+/alanine symporter; COG1115.
      
 0.533
smi_1426
Sodium-dependent transporter; COG0733, SNF family; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.531
smi_1609
Type I restriction-modification system DNA methylase; COG0286.
      
 0.519
guaA
GMP-synthase; Catalyzes the synthesis of GMP from XMP.
      
 0.502
rpsI
30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
      
 0.501
rplL
50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
      
 0.498
smi_1811
Conserved hypothetical protein.
       0.461
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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