Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
smi_1691Transcriptional regulator; COG1725. (117 aa)    
Predicted Functional Partners:
smi_0580
ABC transporter, ATP binding domain, ABC-type multidrug transport system-unknown substrate; COG1131.
 
    0.859
smi_0579
ABC transporter, permease.
 
  
 0.845
nadR
Bifunctional NadR protein; COG3172, NadR, predicted ATPase/kinase involved in NAD metabolism.
   
    0.686
smi_1692
Transposase orfA, IS1381.
       0.538
smi_0256
ABC transporter, ATP-binding protein.
  
    0.471
smi_1871
ABC tranporter, ATP-binding protein; COG1131, CcmA, multidrug transport system.
  
    0.471
smi_1693
Transposase orfB, IS1381; COG3293.
       0.469
smi_1690
Transposase, IS1167, truncation; COG3464.
       0.404
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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