Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smi_1694Conserved hypothetical protein; Excreted protein, signal peptide type I collagen-binding surface protein. (252 aa)    
Predicted Functional Partners:
smi_1696
Conserved hypothetical protein.
 
     0.820
smi_1695
Conserved hypothetical protein; COG0791, cell wall-associated hydrolases, PECACE domain.
 
     0.664
smi_1329
Conserved hypothetical protein.
  
     0.554
smi_1697
Transcriptional regulator, AraC family.
 
     0.543
smi_1325
Conserved hypothetical protein.
  
     0.525
smi_1330
ATP/GTP-binding protein; COG0433, predicted ATPase.
 
     0.469
smi_1698
ABC-type multidrug transport system, ATPase and permease components; COG1132.
 
     0.450
smi_1323
Conserved hypothetical protein; Pfam01580, FtsK/SpoIIIE family.
  
     0.424
smi_1324
Transcriptional regulator, Tn916; COG2946, phage replication protein, helix-turn-helix.
  
     0.417
smi_0124
ABC transporter, ATP-binding protein.
  
     0.411
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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