Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
shetAExfoliative toxin A. (299 aa)    
Predicted Functional Partners:
smi_1721
Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
       0.680
smi_1933
Transcriptional regulator; Pfam04397, LytTr DNA-binding domain.
      
 0.604
smi_1995
ABC transporter permease, sugar transport; COG1175; ABC-type polysaccharide transport system.
      
 0.535
smi_1009
Formate/nitrate transporter; COG2116, FocA.
      
 0.533
smi_1574
Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.
      
 0.531
smi_1719
Transcriptional regulator, TetR family; COG1309.
       0.453
smi_0660
Esterase of alpha/beta hydrolase superfamily.
   
    0.442
smi_1352
Hydrolase; COG2819, predicted hydrolase of the alpha/beta superfamily.
   
    0.442
smi_1990
Conserved hypothetical protein; Cd01518, rhodanese homology domain superfamily; Belongs to the UPF0176 family.
       0.436
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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