smi_1726 protein (Streptococcus mitis) - STRING interaction network

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Score

smi_1726

Conserved hypothetical protein. (267 aa)

Predicted Functional Partners:

cbp12

0.461

cbp13

0.461

smi_1727

0.429

grpE-2

0.414

smi_1729

0.414

smi_1730

0.407

smi_1731

0.407

Your Current Organism:

Streptococcus mitis

NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cbp12	cbp13	smi_1724	smi_1725	Choline binding protein cbp12; COG5263, glucan-binding domain (YG repeat).	COG5263, glucan-binding domain (YG repeat).	0.795
cbp12	smi_1726	smi_1724	smi_1726	Choline binding protein cbp12; COG5263, glucan-binding domain (YG repeat).	Conserved hypothetical protein.	0.461
cbp13	cbp12	smi_1725	smi_1724	COG5263, glucan-binding domain (YG repeat).	Choline binding protein cbp12; COG5263, glucan-binding domain (YG repeat).	0.795
cbp13	smi_1726	smi_1725	smi_1726	COG5263, glucan-binding domain (YG repeat).	Conserved hypothetical protein.	0.461
grpE-2	smi_1726	smi_1728	smi_1726	grpE domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...]	Conserved hypothetical protein.	0.414
grpE-2	smi_1727	smi_1728	smi_1727	grpE domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...]	Conserved hypothetical protein.	0.743
grpE-2	smi_1729	smi_1728	smi_1729	grpE domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...]	dnaJ domain protein; Chaperone, tetratricopeptide repeat domain, homology to DnaJ.	0.777
grpE-2	smi_1730	smi_1728	smi_1730	grpE domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...]	HSP70 family protein; Chaperone, homology to DnaK, COG0443; Belongs to the heat shock protein 70 family.	0.978
grpE-2	smi_1731	smi_1728	smi_1731	grpE domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...]	Conserved hypothetical protein.	0.757
smi_1726	cbp12	smi_1726	smi_1724	Conserved hypothetical protein.	Choline binding protein cbp12; COG5263, glucan-binding domain (YG repeat).	0.461
smi_1726	cbp13	smi_1726	smi_1725	Conserved hypothetical protein.	COG5263, glucan-binding domain (YG repeat).	0.461
smi_1726	grpE-2	smi_1726	smi_1728	Conserved hypothetical protein.	grpE domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...]	0.414
smi_1726	smi_1727	smi_1726	smi_1727	Conserved hypothetical protein.	Conserved hypothetical protein.	0.429
smi_1726	smi_1729	smi_1726	smi_1729	Conserved hypothetical protein.	dnaJ domain protein; Chaperone, tetratricopeptide repeat domain, homology to DnaJ.	0.414
smi_1726	smi_1730	smi_1726	smi_1730	Conserved hypothetical protein.	HSP70 family protein; Chaperone, homology to DnaK, COG0443; Belongs to the heat shock protein 70 family.	0.407
smi_1726	smi_1731	smi_1726	smi_1731	Conserved hypothetical protein.	Conserved hypothetical protein.	0.407
smi_1727	grpE-2	smi_1727	smi_1728	Conserved hypothetical protein.	grpE domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...]	0.743
smi_1727	smi_1726	smi_1727	smi_1726	Conserved hypothetical protein.	Conserved hypothetical protein.	0.429
smi_1727	smi_1729	smi_1727	smi_1729	Conserved hypothetical protein.	dnaJ domain protein; Chaperone, tetratricopeptide repeat domain, homology to DnaJ.	0.743
smi_1727	smi_1730	smi_1727	smi_1730	Conserved hypothetical protein.	HSP70 family protein; Chaperone, homology to DnaK, COG0443; Belongs to the heat shock protein 70 family.	0.727