Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
natAABC transporter ATP-binding protein, Na+ export; COG4555, NatA, ABC-type Na+ transport system, quorum sensing regulated. (297 aa)    
Predicted Functional Partners:
natB
ABC transporter permease, Na+ export; COG1668, NatB, ABC-type Na+ efflux pump, quorum sensing regulated.
 
 
 0.998
smi_1871
ABC tranporter, ATP-binding protein; COG1131, CcmA, multidrug transport system.
    
0.624
ecfA
ABC transporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
    
0.578
dprA
DNA processing protein DprA; COG0758, predicted Rossmann fold nucleotide-binding protein involved in DNA uptake, Smf family.
      
 0.531
smi_0548
Type II secretory pathway, prepilin signal peptidase; COG1989.
      
 0.516
smi_1255
Conserved hypothetical protein; COG1078, phosphohydrolase, HD superfamily.
  
    0.515
pheT
phenylalanyl-tRNA synthetase, beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.464
smi_1588
ABC-type polar amino acid transport system, ATPase component, glutamine transport; COG1126.
 
     
0.416
ecfA-2
ABCtransporter ATP-binding protein cobalt transport; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
    
0.411
Your Current Organism:
Streptococcus mitis
NCBI taxonomy Id: 365659
Other names: S. mitis B6, Streptococcus mitis B6, Streptococcus mitis str. B6, Streptococcus mitis strain B6
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